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| 22 Aug 2014 03:29 PM |
Hypervitaminosis A refers to any number of a large amount of toxic effects from ingesting too much preformed Vitamin A. Symptoms may result from effects including, but not limited to, altered bone metabolism and altered metabolism of other fat-soluble vitamins. Hypervitaminosis A is believed to have occurred in early humans and the problem persists up until the current day.
Toxicity may result from ingesting too much preformed Vitamin A from the diet, supplement intake or prescription medication and can be prevented by not ingesting more than guideline amounts.
Diagnosis is difficult as serum retinol is not sensitive to toxic levels of Vitamin A, although some tests are available. Hypervitaminosis A is usually treated by stopping high Vitamin A intake. Most people fully recover.
High intake of Provitamin carotenoids, such as beta-Carotene, do not cause Hypervitaminosis A as conversion to the active form of Vitamin A is highly regulated.
Contents [hide] 1 Signs and symptoms 2 Causes 2.1 Types of Vitamin A 2.2 Sources of toxicity 2.3 Types of toxicity 3 Mechanism 3.1 Delivery to tissues 3.2 Effects 4 Diagnosis 4.1 Tests 4.2 Relevance of blood tests 5 Prevention 5.1 Daily Tolerable Upper Level 6 Treatment 6.1 In humans 6.2 In animals 6.3 In vitro 7 History 8 Other animals 9 See also 10 References 11 External links Signs and symptoms[edit] Symptoms may include:[1]
Abnormal softening of the skull bone (craniotabes—infants and children) Blurred vision Bone pain or swelling Bulging fontanelle (infants) Changes in consciousness Decreased appetite Dizziness Double vision (young children) Drowsiness Headache Gastric Mucosal Calcinosis (GMC)[2] Heart valve calcification[3] Hypercalcemia Increased intracranial pressure[4] (may be referred to as Idiopathic intracranial hypertension) Irritability Liver damage[5][6][7][8][9][10][11][12][13] Nausea Poor weight gain (infants and children) Skin and hair changes Cracking at corners of the mouth Hair loss Higher sensitivity to sunlight Oily skin and hair (seborrhea) Premature epiphyseal closure[14][15][16][17][18] Skin peeling, itching Spontaneous fracture[19][20] Yellow discoloration of the skin Uremic Pruritus[21] Vision changes Vomiting |
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| 22 Aug 2014 03:29 PM |
| So scientific I can't even |
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Fazana
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| Joined: 21 Feb 2009 |
| Total Posts: 28722 |
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| 22 Aug 2014 03:31 PM |
Let me shorten that down to a single sentence:
Do NOT eat sugar free gummy bears unless you want to spend an entire day destroying a toilet with your butt hole.
~Another post by the pessimistic, cake munching Brit.~ @InsanityBrit |
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